Detail
Localization |
Tissue |
Validated Method |
PMID |
Axon |
Neuron ball cultures |
Fluorescence in situ hybridization |
23897634 |
Description: We used LNA probes for FISH analyses to validate the localization of the above axon-enriched miRNAs shown to be associated with the RISC in vivo. FISH signals of miR-181a-1* (passenger strand of miR-181a-1) and miR-532, two axon-enriched miRNAs (Table 1), distributed as distinct granules in axons and growth cones as well as cell bodies in cultured cortical neurons [Fig. 3(A)].We used LNA probes for FISH analyses to validate the localization of the above axon-enriched miRNAs shown to be associated with the RISC in vivo. FISH signals of miR-181a-1* (passenger strand of miR-181a-1) and miR-532, two axon-enriched miRNAs (Table 1), distributed as distinct granules in axons and growth cones as well as cell bodies in cultured cortical neurons [Fig. 3(A)]. Data are collected from Table 1.
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Other Subcellular Localization:
RLID |
Localization |
Tissue |
Validated Method |
PMID |