Detail
| RLID: | RLID00032281 |
| RNA Symbol: | rno-miR-134-5p |
| RNA Category: | miRNA |
| Organism: | Rattus norvegicus |
| Aliase: | rno-miR-134 |
| Subcellular Localization: | |
| Localization | Tissue | Validated Method | PMID |
| Dendrite | Hippocampus | In situ hybridization | 16421561 |
| Description: Here we show that a brain-specific microRNA, miR-134, is localized to the synaptodendritic compartment of rat hippocampal neurons and negatively regulates the size of dendritic spines 鈥?postsynapticsites of excitatory synaptic transmission. A substantial fraction of the dendritic miR-134 was found to partially colocalize with synapsin immunostaining, indicating that miR-134 is present near synaptic sites on dendrites (Fig. 1d, lower panel and inset at higher magnification). | |||
Other Subcellular Localization:
| RLID | Localization | Tissue | Validated Method | PMID |