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| EWAS ID | GO ID | Class | Disease/Phenotype [sample size n] |
Sample groups (case/control, trait, cell type etc.) |
Categories | GO Term Name | GO Term Gene Number | Gene Number Annotated In The GO Term | Pvalue | |
| Group1 [sample size n] |
Group2 [sample size n] |
|||||||||
| EWAS1296 | GO:0007160 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
biological_process | cell-matrix adhesion | 103 | 91 | 0.000000 |
| EWAS1296 | GO:0007166 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
biological_process | cell surface receptor linked signaling pathway | 1811 | 1415 | 0.000000 |
| EWAS1296 | GO:0007167 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
biological_process | enzyme linked receptor protein signaling pathway | 723 | 592 | 0.000000 |
| EWAS1296 | GO:0007179 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
biological_process | transforming growth factor beta receptor signaling pathway | 106 | 89 | 0.000070 |
| EWAS1296 | GO:0050431 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
molecular_function | transforming growth factor beta binding | 10 | 10 | 0.000000 |
| EWAS1296 | GO:0007187 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
biological_process | G-protein signaling, coupled to cyclic nucleotide second messenger | 134 | 108 | 0.000468 |
| EWAS1296 | GO:0007188 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
biological_process | G-protein signaling, coupled to cAMP nucleotide second messenger | 99 | 82 | 0.000328 |
| EWAS1296 | GO:0007189 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
biological_process | activation of adenylate cyclase activity by G-protein signaling pathway | 41 | 36 | 0.000940 |
| EWAS1296 | GO:0007190 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
biological_process | activation of adenylate cyclase activity | 55 | 49 | 0.000070 |
| EWAS1296 | GO:0007200 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
biological_process | activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupl | 51 | 45 | 0.000223 |