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| EWAS ID | GO ID | Class | Disease/Phenotype [sample size n] |
Sample groups (case/control, trait, cell type etc.) |
Categories | GO Term Name | GO Term Gene Number | Gene Number Annotated In The GO Term | Pvalue | |
| Group1 [sample size n] |
Group2 [sample size n] |
|||||||||
| EWAS1296 | GO:0017076 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
molecular_function | purine nucleotide binding | 1736 | 1331 | 0.000000 |
| EWAS1296 | GO:0030414 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
molecular_function | peptidase inhibitor activity | 152 | 124 | 0.000071 |
| EWAS1296 | GO:0017119 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
cellular_component | Golgi transport complex | 10 | 10 | 0.000000 |
| EWAS1296 | GO:0017124 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
molecular_function | SH3 domain binding | 108 | 89 | 0.000288 |
| EWAS1296 | GO:0017127 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
molecular_function | cholesterol transporter activity | 12 | 12 | 0.000000 |
| EWAS1296 | GO:0019899 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
molecular_function | enzyme binding | 697 | 550 | 0.000000 |
| EWAS1296 | GO:0017156 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
biological_process | calcium ion-dependent exocytosis | 38 | 34 | 0.000502 |
| EWAS1296 | GO:0017157 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
biological_process | regulation of exocytosis | 49 | 45 | 0.000016 |
| EWAS1296 | GO:0017158 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
biological_process | regulation of calcium ion-dependent exocytosis | 20 | 19 | 0.000478 |
| EWAS1296 | GO:0017171 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
molecular_function | serine hydrolase activity | 156 | 133 | 0.000000 |