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| EWAS ID | GO ID | Class | Disease/Phenotype [sample size n] |
Sample groups (case/control, trait, cell type etc.) |
Categories | GO Term Name | GO Term Gene Number | Gene Number Annotated In The GO Term | Pvalue | |
| Group1 [sample size n] |
Group2 [sample size n] |
|||||||||
| EWAS71 | GO:0050431 | disease | head and neck squamous cell cancer (HNSCC) [n=24] |
human neck squamous cell carcinoma (HNSCC)? [n=12] |
Normal [n=12] |
molecular_function | transforming growth factor beta binding | 10 | 10 | 0.000000 |
| EWAS71 | GO:0007186 | disease | head and neck squamous cell cancer (HNSCC) [n=24] |
human neck squamous cell carcinoma (HNSCC)? [n=12] |
Normal [n=12] |
biological_process | G-protein coupled receptor protein signaling pathway | 532 | 464 | 0.000000 |
| EWAS71 | GO:0007187 | disease | head and neck squamous cell cancer (HNSCC) [n=24] |
human neck squamous cell carcinoma (HNSCC)? [n=12] |
Normal [n=12] |
biological_process | G-protein signaling- coupled to cyclic nucleotide second messenger | 134 | 121 | 0.000034 |
| EWAS71 | GO:0007188 | disease | head and neck squamous cell cancer (HNSCC) [n=24] |
human neck squamous cell carcinoma (HNSCC)? [n=12] |
Normal [n=12] |
biological_process | G-protein signaling- coupled to cAMP nucleotide second messenger | 99 | 93 | 0.000002 |
| EWAS71 | GO:0007189 | disease | head and neck squamous cell cancer (HNSCC) [n=24] |
human neck squamous cell carcinoma (HNSCC)? [n=12] |
Normal [n=12] |
biological_process | activation of adenylate cyclase activity by G-protein signaling pathway | 41 | 39 | 0.000385 |
| EWAS71 | GO:0007190 | disease | head and neck squamous cell cancer (HNSCC) [n=24] |
human neck squamous cell carcinoma (HNSCC)? [n=12] |
Normal [n=12] |
biological_process | activation of adenylate cyclase activity | 55 | 52 | 0.000120 |
| EWAS71 | GO:0007193 | disease | head and neck squamous cell cancer (HNSCC) [n=24] |
human neck squamous cell carcinoma (HNSCC)? [n=12] |
Normal [n=12] |
biological_process | inhibition of adenylate cyclase activity by G-protein signaling pathway | 44 | 43 | 0.000014 |
| EWAS71 | GO:0007194 | disease | head and neck squamous cell cancer (HNSCC) [n=24] |
human neck squamous cell carcinoma (HNSCC)? [n=12] |
Normal [n=12] |
biological_process | negative regulation of adenylate cyclase activity | 57 | 56 | 0.000001 |
| EWAS71 | GO:0007202 | disease | head and neck squamous cell cancer (HNSCC) [n=24] |
human neck squamous cell carcinoma (HNSCC)? [n=12] |
Normal [n=12] |
biological_process | activation of phospholipase C activity | 102 | 94 | 0.000023 |
| EWAS71 | GO:0007204 | disease | head and neck squamous cell cancer (HNSCC) [n=24] |
human neck squamous cell carcinoma (HNSCC)? [n=12] |
Normal [n=12] |
biological_process | elevation of cytosolic calcium ion concentration | 134 | 127 | 0.000000 |