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| EWAS ID | GO ID | Class | Disease/Phenotype [sample size n] |
Sample groups (case/control, trait, cell type etc.) |
Categories | GO Term Name | GO Term Gene Number | Gene Number Annotated In The GO Term | Pvalue | |
| Group1 [sample size n] |
Group2 [sample size n] |
|||||||||
| EWAS717 | GO:0005886 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
cellular_component | plasma membrane | 3859 | 2605 | 0.000000 |
| EWAS717 | GO:0000122 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
biological_process | negative regulation of transcription from RNA polymerase II promoter | 365 | 258 | 0.000070 |
| EWAS717 | GO:0000139 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
cellular_component | Golgi membrane | 460 | 314 | 0.000795 |
| EWAS717 | GO:0000166 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
molecular_function | nucleotide binding | 2141 | 1429 | 0.000000 |
| EWAS717 | GO:0000187 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
biological_process | activation of MAPK activity | 101 | 77 | 0.000511 |
| EWAS717 | GO:0005515 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
molecular_function | protein binding | 6808 | 4547 | 0.000000 |
| EWAS717 | GO:0005622 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
cellular_component | intracellular | 11029 | 7025 | 0.000000 |
| EWAS717 | GO:0000267 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
cellular_component | cell fraction | 1041 | 732 | 0.000000 |
| EWAS717 | GO:0000323 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
cellular_component | lytic vacuole | 260 | 188 | 0.000075 |
| EWAS717 | GO:0000768 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
biological_process | syncytium formation by plasma membrane fusion | 12 | 12 | 0.000000 |