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| EWAS ID | EWAS522 |
| GSE ID | GSE63695 |
| EWAS Title | Characterization of the cartilage DNA methylome in knee and hip osteoarthritis. |
| Disease/Phenotype | osteoarthritis (OA) |
| Group1 | Normal(Hip cartilage) |
| Group2 | osteoarthritis(Knee cartilage) |
| Group1 Sample Size | 19 |
| Group2 Sample Size | 62 |
| Summary | The aim of this study was to characterise the genome-wide DNA methylation profile of osteoathritis (OA) chondrocytes from both knee and hip cartilage, providing the first comparison of DNA methylation between OA and non-OA hip cartilage, and between OA hip and OA knee cartilage. The study was performed using the Illumina Infinium HumanMethylation450 BeadChip array. Genome-wide methylation was assesed in chondrocyte DNA extracted from 23 OA hip, 73 OA knee and 21 healthy hip controls (NOF - neck of femure samples). Keywords: Methylation profiling by array |
| Contributor | Skelton AJ, Reynard LN, Loughlin J, Rushton MD |
| Public date | Public on Sep 02, 2015 |
| Citation (PubMed ID) | 24838673 |
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