The query results for rs1801131 , total 12 literatures
There are some abbreviations existing in the query results. For example, RA is an abbreviation for rheumatoid arthritis, H is an abbreviation for healthy controls...more

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Pubmed_ID Title Country Population

15361376
Methotrexate related adverse effects in patients with rheumatoid arthritis are associated with the A1298C polymorphism of the MTHFR gene.
 Israel Asian

16439441
Racial or ethnic differences in allele frequencies of single-nucleotide polymorphisms in the methylenetetrahydrofolate reductase gene and their influence on response to methotrexate in rheumatoid arthritis.
 US American

18034620
677C>T and 1298A>C MTHFR polymorphisms affect methotrexate treatment outcome in rheumatoid arthritis.
 Poland European

18195462
677C > T and 1298A > C MTHFR polymorphisms affect arechin treatment outcome in rheumatoid arthritis.
 Poland European

18274813
Are Thymidylate synthase and Methylene tetrahydrofolate reductase genes linked with methotrexate response (efficacy, toxicity) in Indian (Asian) rheumatoid arthritis patients?
 India Asian

18322994
Common polymorphisms in the folate pathway predict efficacy of combination regimens containing methotrexate and sulfasalazine in early rheumatoid arthritis.
 Australia Oceanian

18607581
Genetic determinants of methotrexate toxicity in rheumatoid arthritis patients: a study of polymorphisms affecting methotrexate transport and folate metabolism.
 Slovenija European

19193698
Investigation of candidate polymorphisms and disease activity in rheumatoid arthritis patients on methotrexate.
 US American

19578646
The effect of 677C>T and 1298A>C MTHFR polymorphisms on sulfasalazine treatment outcome in rheumatoid arthritis.
 Poland European

19604445
Methylenetetrahydrofolate reductase polymorphisms and methotrexate: no association with response to therapy nor with drug-related adverse events in an Italian population of rheumatic patients.
 Italy European

19827168
Genetic polymorphisms in folate pathway enzymes as a possible marker for predicting the outcome of methotrexate therapy in Japanese patients with rheumatoid arthritis.
 Japan Asian

20423475
A1298C polymorphism in the MTHFR gene predisposes to cardiovascular risk in rheumatoid arthritis.
 Spain European

Risk allele : People who carry this allele have a higher risk of developing rheumatoid arthritis than those without this allele.
Related allele in clinical features : Patients with rheumatoid arthritis who carry this allele have different clinical features (such as RF status, ACCP status, age of onset) compared to those without this allele.
Related allele in pharmacogenomics : Patients with rheumatoid arthritis carry this allele are less responsive to drug treatment than those without this allele.
Related allele in cardiovascular (CV) disease : RA patients with this allele have a higher risk of developing CV events than those without this allele.
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