The query results for rs2228145 , total 4 literatures
There are some abbreviations existing in the query results. For example, RA is an abbreviation for rheumatoid arthritis, H is an abbreviation for healthy controls...more

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Pubmed_ID Title Country Population

19713205
A gain of function polymorphism in the interleukin 6 receptor influences RA susceptibility.
 UK European

19926672
Genotype at the sIL-6R A358C polymorphism does not influence response to anti-TNF therapy in patients with rheumatoid arthritis.
 UK European

23143596
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
 Sweden,Holland,Spain,US,Canada,UK European

23148991
Association analysis of single nucleotide polymorphisms of proinflammatory cytokine and their receptors genes with rheumatoid arthritis in northwest Chinese Han population.
 China Asian

Risk allele : People who carry this allele have a higher risk of developing rheumatoid arthritis than those without this allele.
Related allele in clinical features : Patients with rheumatoid arthritis who carry this allele have different clinical features (such as RF status, ACCP status, age of onset) compared to those without this allele.
Related allele in pharmacogenomics : Patients with rheumatoid arthritis carry this allele are less responsive to drug treatment than those without this allele.
Related allele in cardiovascular (CV) disease : RA patients with this allele have a higher risk of developing CV events than those without this allele.
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