The query results for rs2488457 , total 4 literatures
There are some abbreviations existing in the query results. For example, RA is an abbreviation for rheumatoid arthritis, H is an abbreviation for healthy controls...more

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Pubmed_ID Title Country Population

17661906
The PTPN22 promoter polymorphism -1123G>C association cannot be distinguished from the 1858C>T association in a Norwegian rheumatoid arthritis material.
 Norway European

18474664
Testing for linkage and association with rheumatoid arthritis a ptpn22 promoter polymorphism reported to be associated and linked with type 1 diabetes in the Caucasian population.
 NA NA

19180477
Genetic risk factors for rheumatoid arthritis differ in Caucasian and Korean populations.
 Korea Asian

20604892
Association of the PTPN22 gene (-1123G > C) polymorphism with rheumatoid arthritis in Chinese patients.
 China Asian

Risk allele : People who carry this allele have a higher risk of developing rheumatoid arthritis than those without this allele.
Related allele in clinical features : Patients with rheumatoid arthritis who carry this allele have different clinical features (such as RF status, ACCP status, age of onset) compared to those without this allele.
Related allele in pharmacogenomics : Patients with rheumatoid arthritis carry this allele are less responsive to drug treatment than those without this allele.
Related allele in cardiovascular (CV) disease : RA patients with this allele have a higher risk of developing CV events than those without this allele.
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