All polymorphisms studied in this paper [PMID: 12610796] , total : 2 polymorphisms

Title : Lack of association between -384 and 114 IL-2 gene polymorphisms and rheumatoid arthritis.

Abstract : OBJECTIVE: To investigate the association of 2 single nucleotide polymorphisms (SNP) at positions -384 and 114 in the human interleukin 2 (IL-2) gene with susceptibility to and severity of rheumatoid arthritis (RA). METHODS: Genotyping for these IL-2 variants was performed by a polymerase chain reaction restriction fragment length polymorphism method in 174 RA patients and 153 control individuals. RESULTS: No statistically significant differences were observed when the -384 and 114 IL-2 genotype distributions between RA patients and healthy controls were compared. In addition, no association was found between the IL-2 genotypes with any demographic and clinical variables tested. CONCLUSION: Our results provide no evidence for genetic association conferred by the -384 and 114 IL-2 SNP with respect to susceptibility and severity of RA.

Author : Fedetz M,Matesanz F,Caliz R,Ferrer MA,Collado MD,Alcina A,Martin J,

Source : J Rheumatol. 2003 Mar;30(3):435-7.

No.	Polymorphism name	Gene Symbol	Entrez Gene ID
1	NA	IL2	3558
2	NA	IL2	3558