All polymorphisms studied in this paper [PMID: 15083890] , total : 1 polymorphisms

Title : Association between urokinase gene 3'-UTR T/C polymorphism and Chinese patients with rheumatoid arthritis in Taiwan.

Abstract : OBJECTIVES: The purpose of this study was to investigate whether the urokinase gene 3'-UTR C/T polymorphism is a marker of susceptibility to or severity of rheumatoid arthritis (RA) in Chinese patients. METHODS: A total of 145 RA patients and 134 healthy control subjects were enrolled in this study. We identified the C/T polymorphism of the urokinase gene, which is mapped on the 3'-untranslated region (3'-UTR) on chromosome 10 by polymerase chain reaction (PCR). RESULTS: There were significant differences in the distribution of the urokinase gene 3'-UTR C/T polymorphism frequency between RA patients and subjects in the control group. However, we did not detect an, association between the urokinase gene 3'-UTR C/T polymorphism and rheumatoid factor (RF), extraarticular involvement or bone erosion in RA patients. CONCLUSION: The urokinase gene 3'-UTR "T" allele was associated with RA in Chinese patients in Taiwan.

Author : Huang CM,Chen CL,Tsai JJ,Tsai CH,Tsai FJ,

Source : Clin Exp Rheumatol. 2004 Mar-Apr;22(2):219-22.

No.	Polymorphism name	Gene Symbol	Entrez Gene ID
1	NA	PLAU	5328