All polymorphisms studied in this paper [PMID: 16216669] , total : 2 polymorphisms

Title : Analysis of vascular endothelial growth factor (VEGF) functional variants in rheumatoid arthritis.

Abstract : The vascular endothelial growth factor (VEGF) is one of the most important pro-angiogenic mediators related to inflammation-associated synovial angiogenesis. The aim of this study was to asses the role of -1154 G-->A (rs1570360) and -634 G-->C (rs2010963) VEGF gene functional variants with rheumatoid arthritis (RA). The population under study was composed of a total of 753 unrelated RA patients and 801 healthy controls. The VEGF -1154 G-->A and -634 G-->C polymorphism genotyping was performed by real-time polymerase chain reaction technology, using TaqMan 5' allelic discrimination assay. No evidence of association was observed between the -1154 G-->A and the -634 G-->C VEGF polymorphisms, or inferred VEGF haplotypes with RA susceptibility or clinical manifestations. Our results suggest that the analyzed VEGF promoter polymorphisms may not play a relevant role in RA pathogenesis in our population.

Author : Rueda B,Gonzalez-Gay MA,Lopez-Nevot MA,Garcia A,Fernandez-Arquero M,Balsa A,Pablos JL,Pascual-Salcedo D,de la Concha EG,Gonzalez-Escribano MF,Martin J,

Source : Hum Immunol. 2005 Aug;66(8):864-8. Epub 2005 Jul 19.

No.	Polymorphism name	Gene Symbol	Entrez Gene ID
1	rs1570360	VEGFA	7422
2	rs2010963	VEGFA	7422