All polymorphisms studied in this paper [PMID: 19567623] , total : 7 polymorphisms

Title : Lack of association with rheumatoid arthritis of selected polymorphisms in 4 candidate genes: CFH, CD209, eotaxin-3, and MHC2TA.

Abstract : OBJECTIVE: To investigate associations with rheumatoid arthritis (RA) of single-nucleotide polymorphisms (SNP) in 4 candidate genes, complement factor H (CFH), CD209 or DC-SIGN, eotaxin-3, and the MHC class II Transactivator (MHC2TA) genes. These SNP have been reported as important for RA (eotaxin-3 and MHC2TA) or for other immune-mediated diseases (CFH and CD209). METHODS: Genotypes for the 7 selected SNP were obtained from 1587 patients with RA and 1570 controls of Spanish ancestry. Analyses were carried out after stratification for sex, erosions, rheumatoid factor, shared epitope, anti-cyclic citrullinated peptide antibodies, and the R620W PTPN22 SNP. RESULTS: None of the comparisons between patients with RA and controls or between the different strata of patients according to disease features was significant. CONCLUSION: None of the SNP in CFH and CD209 showed evidence of association with RA. We did not replicate the association of eotaxin-3 with RA described in Koreans, or that of the MHC2T SNP.

Author : Dieguez-Gonzalez R,Akar S,Calaza M,Gonzalez-Alvaro I,Fernandez-Gutierrez B,Lamas JR,de la Serna AR,Caliz R,Blanco FJ,Pascual-Salcedo D,Velloso ML,Perez-Pampin E,Pablos JL,Navarro F,Narvaez J,Lopez-Longo FJ,Herrero-Beaumont G,Gomez-Reino JJ,Gonzalez A,

Source : J Rheumatol. 2009 Aug;36(8):1590-5. doi: 10.3899/jrheum.090022. Epub 2009 Jun 30.

No.	Polymorphism name	Gene Symbol	Entrez Gene ID
1	rs8002209	NA	NA
2	rs3766404	CFH	3075
3	rs1061170	CFH	3075
4	rs4804803	CD209	30835
5	rs2302009	CCL26	10344
6	rs6965556	CCL26	10344
7	rs3087456	CIITA	4261