All polymorphisms studied in this paper [PMID: 19744146] , total : 13 polymorphisms
| Title : IL7RA polymorphisms and chronic inflammatory arthropathies. |
| Abstract : The C allele of a single nucleotide polymorphism (SNP), rs6897932, located in the interleukin-7 receptor alpha chain (IL7RA) was recently found to be associated with multiple sclerosis and Type I diabetes. We analysed 13 SNPs in the IL7RA gene in a combined cohort of patients with chronic inflammatory arthropathies (rheumatoid arthritis and juvenile idiopathic arthritis; 368 patients and 532 unaffected subjects). No significant associations with disease were found with the exception of the non-synonymous SNP rs6897932. This SNP showed modest enrichment of the TT genotype in arthritic patients compared with controls [P = 0.02; OR 1.72 (95% CI 1.08-2.75)]. Our data are suggestive for a role of rs6897932 in predisposition to chronic inflammatory arthropathies. |
| Author : O'Doherty C,Alloza I,Rooney M,Vandenbroeck K, |
| Source : Tissue Antigens. 2009 Nov;74(5):429-31. doi: 10.1111/j.1399-0039.2009.01342.x. Epub 2009 Sep 8. |
13 records 1/1 page
| No. | Polymorphism name | Gene Symbol | Entrez Gene ID |
|---|---|---|---|
| 1 | rs11567697 | IL7R | 3575 |
| 2 | rs7711202 | IL7R | 3575 |
| 3 | rs11567773 | IL7R | 3575 |
| 4 | rs11567751 | IL7R | 3575 |
| 5 | rs11567762 | IL7R | 3575 |
| 6 | rs1494554 | IL7R | 3575 |
| 7 | rs6897932 | IL7R | 3575 |
| 8 | rs3822733 | IL7R | 3575 |
| 9 | rs987107 | IL7R | 3575 |
| 10 | rs11567777 | IL7R | 3575 |
| 11 | rs3194051 | IL7R | 3575 |
| 12 | rs10491434 | IL7R | 3575 |
| 13 | rs1389835 | NA | NA |
13 records 1/1 page
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