All polymorphisms studied in this paper [PMID: 21159834] , total : 1 polymorphisms

Title : The functional polymorphism 844 A>G in FcalphaRI (CD89) does not contribute to systemic sclerosis or rheumatoid arthritis susceptibility.

Abstract : OBJECTIVE: To investigate the role of the Fc(alpha)RI 844 A>G functional polymorphism in the genetic predisposition to rheumatoid arthritis (RA) and systemic sclerosis (SSc) susceptibility. METHODS: The study population was composed of 1401 patients with SSc, 642 patients with RA, and 1317 healthy controls. The Fc(alpha)RI (CD89) single-nucleotide polymorphism rs16986050 was genotyped by pyrosequencing. RESULTS: We observed no significant deviation of the genotype and allele frequencies in RA and SSc compared to controls. A metaanalysis and a recessive and dominant model yielded similar negative results. CONCLUSION: Our data show that the Fc(alpha)RI 844 A>G polymorphism is not associated with SSc or RA susceptibility.

Author : Broen JC,Coenen MJ,Rueda B,Witte T,Padyukov L,Klareskog L,Hesselstrand R,Wuttge DM,Simeon C,Ortego-Centeno N,Gonzalez-Gay MA,Pros A,Hunzelman N,Riemekasten G,Kreuter A,Vonk M,Scorza R,Beretta L,Airo P,van Riel PL,Kimberly R,Martin J,Edberg J,Radstake TR,

Source : J Rheumatol. 2011 Mar;38(3):446-9. doi: 10.3899/jrheum.100427. Epub 2010 Dec 15.

No.	Polymorphism name	Gene Symbol	Entrez Gene ID
1	rs16986050	FCAR	2204