All polymorphisms studied in this paper [PMID: 24498997] , total : 2 polymorphisms

Title : Single-nucleotide polymorphisms at the 9p21.3 genomic region not associated with the risk of cardiovascular disease in patients with rheumatoid arthritis.

Abstract : Rheumatoid arthritis (RA) is a chronic polygenic inflammatory disease associated with accelerated atherosclerosis and high risk of cardiovascular disease (CVD). In this study, we evaluated the potential association of 9p21.3 single-nucleotide polymorphisms (SNPs) - previously linked to coronary artery disease - and CVD risk in 2001 Spanish RA patients genotyped for 9p21.3 SNPs using TaqMan assays. Carotid intima media thickness (cIMT) and presence of carotid plaques were also analyzed. Cox regression model did not disclose significant differences between patients who experienced CVD and those who did not. Neither association was found between cIMT or carotid plaques and SNPs allele distribution. In conclusion, results do not support a role of rs10116277 or rs1537375 SNPs in CVD risk in Spanish RA patients.

Author : Garcia-Bermudez M,Lopez-Mejias R,Genre F,Castaneda S,Gonzalez-Juanatey C,Llorca J,Corrales A,Miranda-Filloy JA,Pina T,Gomez-Vaquero C,Rodriguez-Rodriguez L,Fernandez-Gutierrez B,Pascual-Salcedo D,Balsa A,Lopez-Longo FJ,Carreira P,Blanco R,Gonzalez-Alvaro I,Martin J,Gonzalez-Gay MA,

Source : Tissue Antigens. 2013 Dec;82(6):405-9. doi: 10.1111/tan.12227. Epub 2013 Oct 15.

No.	Polymorphism name	Gene Symbol	Entrez Gene ID
1	rs10116277	CDKN2B-AS1	100048912
2	rs1537375	CDKN2B-AS1	100048912