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| EWAS ID | GO ID | Class | Disease/Phenotype [sample size n] |
Sample groups (case/control, trait, cell type etc.) |
Categories | GO Term Name | GO Term Gene Number | Gene Number Annotated In The GO Term | Pvalue | |
| Group1 [sample size n] |
Group2 [sample size n] |
|||||||||
| EWAS1296 | GO:0007165 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
biological_process | signal transduction | 3332 | 2575 | 0.000000 |
| EWAS1296 | GO:0019838 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
molecular_function | growth factor binding | 109 | 97 | 0.000000 |
| EWAS1296 | GO:0005044 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
molecular_function | scavenger receptor activity | 42 | 38 | 0.000145 |
| EWAS1296 | GO:0005783 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
cellular_component | endoplasmic reticulum | 1027 | 760 | 0.000017 |
| EWAS1296 | GO:0005057 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
molecular_function | receptor signaling protein activity | 94 | 78 | 0.000388 |
| EWAS1296 | GO:0007169 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
biological_process | transmembrane receptor protein tyrosine kinase signaling pathway | 539 | 446 | 0.000000 |
| EWAS1296 | GO:0035556 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
biological_process | intracellular signal transduction | 1579 | 1251 | 0.000000 |
| EWAS1296 | GO:0007178 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
biological_process | transmembrane receptor protein serine/threonine kinase signaling pathway | 178 | 141 | 0.000398 |
| EWAS1296 | GO:0008104 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
biological_process | protein localization | 1082 | 790 | 0.000214 |
| EWAS1296 | GO:0005083 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
molecular_function | small GTPase regulator activity | 276 | 221 | 0.000004 |