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| EWAS ID | GO ID | Class | Disease/Phenotype [sample size n] |
Sample groups (case/control, trait, cell type etc.) |
Categories | GO Term Name | GO Term Gene Number | Gene Number Annotated In The GO Term | Pvalue | |
| Group1 [sample size n] |
Group2 [sample size n] |
|||||||||
| EWAS1296 | GO:0006936 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
biological_process | muscle contraction | 203 | 176 | 0.000000 |
| EWAS1296 | GO:0043292 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
cellular_component | contractile fiber | 121 | 105 | 0.000001 |
| EWAS1296 | GO:0003779 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
molecular_function | actin binding | 311 | 264 | 0.000000 |
| EWAS1296 | GO:0030674 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
molecular_function | protein binding, bridging | 98 | 85 | 0.000006 |
| EWAS1296 | GO:0051015 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
molecular_function | actin filament binding | 54 | 48 | 0.000094 |
| EWAS1296 | GO:0030036 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
biological_process | actin cytoskeleton organization | 278 | 229 | 0.000000 |
| EWAS1296 | GO:0016020 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
cellular_component | membrane | 7148 | 5382 | 0.000000 |
| EWAS1296 | GO:0006952 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
biological_process | defense response | 828 | 645 | 0.000000 |
| EWAS1296 | GO:0006953 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
biological_process | acute-phase response | 44 | 39 | 0.000393 |
| EWAS1296 | GO:0004252 | disease | multiple sclerosis [n=96] |
multiple sclerosis patients treated with fumaric acid esters(FAE) [n=42] |
untreated/treatment naive multiple sclerosis patients(Naive) [n=54] |
molecular_function | serine-type endopeptidase activity | 130 | 113 | 0.000000 |