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| EWAS ID | GO ID | Class | Disease/Phenotype [sample size n] |
Sample groups (case/control, trait, cell type etc.) |
Categories | GO Term Name | GO Term Gene Number | Gene Number Annotated In The GO Term | Pvalue | |
| Group1 [sample size n] |
Group2 [sample size n] |
|||||||||
| EWAS717 | GO:0005856 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
cellular_component | cytoskeleton | 1439 | 971 | 0.000000 |
| EWAS717 | GO:0005892 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
cellular_component | nicotinic acetylcholine-gated receptor-channel complex | 17 | 16 | 0.000247 |
| EWAS717 | GO:0005912 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
cellular_component | adherens junction | 151 | 122 | 0.000000 |
| EWAS717 | GO:0005924 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
cellular_component | cell-substrate adherens junction | 105 | 85 | 0.000004 |
| EWAS717 | GO:0005925 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
cellular_component | focal adhesion | 100 | 83 | 0.000001 |
| EWAS717 | GO:0006140 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
biological_process | regulation of nucleotide metabolic process | 291 | 206 | 0.000284 |
| EWAS717 | GO:0006357 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
biological_process | regulation of transcription from RNA polymerase II promoter | 890 | 598 | 0.000100 |
| EWAS717 | GO:0006464 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
biological_process | protein modification process | 2019 | 1340 | 0.000000 |
| EWAS717 | GO:0006468 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
biological_process | protein phosphorylation | 999 | 704 | 0.000000 |
| EWAS717 | GO:0006629 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
biological_process | lipid metabolic process | 920 | 628 | 0.000004 |