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| EWAS ID | KEGG ID | Class | Disease/Phenotype [sample size n] |
Sample groups (case/control, trait, cell type etc.) |
KEGG Pathway Name | Pathway Gene Number | Gene Number Annotated In The KEGG Pathway | Pvalue | |
| Group1 [sample size n] |
Group2 [sample size n] |
||||||||
| EWAS717 | hsa04010 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
MAPK signaling pathway | 251 | 177 | 0.000924 |
| EWAS717 | hsa04014 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Ras signaling pathway | 226 | 173 | 3.74e-007 |
| EWAS717 | hsa04015 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Rap1 signaling pathway | 211 | 170 | 4.73e-010 |
| EWAS717 | hsa04020 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Calcium signaling pathway | 178 | 135 | 1.38e-005 |
| EWAS717 | hsa04060 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Cytokine-cytokine receptor interaction | 249 | 177 | 0.000494 |
| EWAS717 | hsa04062 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Chemokine signaling pathway | 187 | 137 | 0.00022 |
| EWAS717 | hsa04144 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Endocytosis | 254 | 186 | 2.36e-005 |
| EWAS717 | hsa04151 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
PI3K-Akt signaling pathway | 332 | 239 | 1.66e-005 |
| EWAS717 | hsa04152 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
AMPK signaling pathway | 122 | 92 | 0.000351 |
| EWAS717 | hsa04270 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Vascular smooth muscle contraction | 120 | 95 | 8.9e-006 |