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| EWAS ID | KEGG ID | Class | Disease/Phenotype [sample size n] |
Sample groups (case/control, trait, cell type etc.) |
KEGG Pathway Name | Pathway Gene Number | Gene Number Annotated In The KEGG Pathway | Pvalue | |
| Group1 [sample size n] |
Group2 [sample size n] |
||||||||
| EWAS717 | hsa04611 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Platelet activation | 129 | 98 | 0.000146 |
| EWAS717 | hsa04640 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Hematopoietic cell lineage | 81 | 63 | 0.00053 |
| EWAS717 | hsa04713 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Circadian entrainment | 95 | 81 | 7.54e-008 |
| EWAS717 | hsa04724 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Glutamatergic synapse | 114 | 89 | 4.44e-005 |
| EWAS717 | hsa04725 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Cholinergic synapse | 111 | 91 | 7.02e-007 |
| EWAS717 | hsa04810 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Regulation of actin cytoskeleton | 212 | 154 | 0.000201 |
| EWAS717 | hsa04916 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Melanogenesis | 100 | 84 | 1.96e-007 |
| EWAS717 | hsa04920 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Adipocytokine signaling pathway | 70 | 57 | 8.32e-005 |
| EWAS717 | hsa04921 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Oxytocin signaling pathway | 157 | 122 | 3.92e-006 |
| EWAS717 | hsa04925 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Aldosterone synthesis and secretion | 81 | 64 | 0.00021 |