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| EWAS ID | KEGG ID | Class | Disease/Phenotype [sample size n] |
Sample groups (case/control, trait, cell type etc.) |
KEGG Pathway Name | Pathway Gene Number | Gene Number Annotated In The KEGG Pathway | Pvalue | |
| Group1 [sample size n] |
Group2 [sample size n] |
||||||||
| EWAS717 | hsa04330 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Notch signaling pathway | 48 | 39 | 0.00086 |
| EWAS717 | hsa04340 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Hedgehog signaling pathway | 50 | 42 | 0.000126 |
| EWAS717 | hsa04360 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Axon guidance | 127 | 94 | 0.000944 |
| EWAS717 | hsa04390 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Hippo signaling pathway | 151 | 113 | 0.000161 |
| EWAS717 | hsa04510 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Focal adhesion | 205 | 152 | 3.86e-005 |
| EWAS717 | hsa04512 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
ECM-receptor interaction | 86 | 66 | 0.000813 |
| EWAS717 | hsa04514 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Cell adhesion molecules (CAMs) | 138 | 107 | 1.63e-005 |
| EWAS717 | hsa04530 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Tight junction | 137 | 101 | 0.000828 |
| EWAS717 | hsa04540 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Gap junction | 88 | 68 | 0.000489 |
| EWAS717 | hsa04550 | disease | down syndrome (DS) [n=23] |
Down syndrome(Adult;Cerebellar cortex;Whole grey matter) [n=13] |
Normal(Adult;Cerebellar cortex;Whole grey matter) [n=10] |
Signaling pathways regulating pluripotency of stem cells | 140 | 104 | 0.000442 |